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Islet Cells
Body

Human islets display unique morphological and functional differences compared to rodent models; therefore, they are a critical resource for better understanding diabetes physiology in humans. Due to limited supply and increased researcher needs, LifeNet Health LifeSciences has begun developing protocols to isolate high-quality human islets.

Isolated human islets stained with fluorescein diacetate (FDA) and propidium iodide (PI)

Islets shown with viability stains FDA and PI

Isolated human islet stained for insulin and glucagon

Islets stained for Insulin and Glucagon

 Isolated human islets on Day 12 of culture stained with diphenylthiocarbazone (DZT)

Islets in Culture stained with diphenylthiocarbazone-Day 12

H&E stained image of human pancreatic tissue showing intact islet

H&E Stained Pancreatic Islet

Immunohistochemical (IHC) stained human pancreatic tissue with islet stained for the secretion of insulin and amylase

Pancreatic Islet cell grouping stained with antibodies for insulin and amylase

Immunohistochemical (IHC) stained human pancreatic tissue with islet stained for the secretion of insulin and glucagon

Pancreatic Islet cell grouping stained with antibodies for insulin and glucagon