Nicky Hewitt, PhD, a consultant with Cosmetics Europe, explains how her skin-liver-thyroid MPS model is being used to support animal-free cosmetics testing.

Key topics include:

• An overview of Cosmetics Europe projects evaluating new approach methodologies for animal-free safety assessment.
• The integration of thyroid follicles into a skin-liver MPS model.
• Why route-specific effects on thyroid hormones are a key endpoint in the safety assessment of cosmetic and environmental chemicals.