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Improving Human Safety Decisions with a Functional In Vitro Thyroid Model

Join Eda Rogers, PhD, Senior Scientist, LifeSciences Research and Development, LifeNet Health LifeSciences, for an in-depth discussion on advancing thyroid toxicity testing through next-generation in vitro models. This webinar will highlight a novel 3D human thyroid microtissue assay designed to more accurately evaluate thyroid-disrupting chemicals by replicating native thyroid function and hormone synthesis. Learn how this new approach methodology (NAM) supports regulatory efforts, improves human relevance, and strengthens risk assessment for endocrine-disrupting compounds.

Key Takeaways:

  • Learn how a 3D human thyrocyte microtissue assay provides a physiologically relevant platform to evaluate thyroid hormone disruption.
  • See how the model demonstrated strong reproducibility, dynamic range, and screening precision, establishing confidence for its use in evaluating thyroid-disrupting chemicals (TDCs).
  • Discover how concentration-response data and statistical benchmarks validate the assay’s robustness for toxicology and chemical screening applications.
  • Learn how this single in vitro assay can assess multiple molecular initiating events (MIEs), enabling researchers to better prioritize compounds and strengthen human health risk assessment efforts.

Guest Speaker: Eda Rogers, PhD, Senior Scientist, LifeSciences Research and Development, LifeNet Health LifeSciences

Speaker Bio:

Eda Rogers, PhD, is a Research & Development Scientist at LifeNet Health LifeSciences. After obtaining her B.S. degree at the Istanbul University in Turkey where she was Valedictorian, Dr. Rogers graduated with her PhD in Biology from the Rensselaer Polytechnic Institute. While at RPI, she received the prestigious Karen and Lester Gerhardt Graduate Student Award in recognition of her outstanding academic achievement. Her research interests include developing primary human cell products for use in drug discovery and development.  Her latest achievement has been to successfully transfer and improve the 3D thyroid microtissues model from our collaborative team at the US Environmental Protection Agency.