Improved Clearance Predictions for Aldehyde Oxidase Substrates Using TruVivo, a Novel Human Hepatocyte Model
In this exclusive session, Stephanie Piekos, PhD, Senior Scientist at Boehringer Ingelheim, shares insights into the challenges of evaluating AO substrates and how more predictive, human-relevant models are shaping the future of DMPK studies.
Key topics:
• Understand the metabolic role and clinical importance of aldehyde oxidase
• Recognize the limitations of traditional models for studying AO-mediated clearance
• Discover how TruVivo enhances AO activity to support more predictive, human-relevant outcomes