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Considerations for Tissue Donation Authorization - the GTEx Case Study

Laura Siminoff, PhD, Dean at the College of Public Health at Temple University, discusses best practices for communicating and obtaining consent from donor families based on experience from the Genotyping-Tissue Expression Project (GTEx). Dr. Siminoff was a key contributor to the project, launched in 2010 by the National Institutes of Health (NIH), which characterized genetic associations across 49 tissues from over 800 postmortem donors. Topics include:

  • Why communication is essential when obtaining authorization from donor families
  • What is required vs. recommended when authorizing tissue donation
  • How the tissue donation and research consent was used for the GTEx project