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Biospecimen Research on Earth and in Space: A Model for Human Osteoarthritis in the Space Shuttle

Alan Grodzinsky, ScD, Director of Massachusetts Institute of Technology’s Center for Biomedical Engineering and Professor of Biological, Electrical, and Mechanical Engineering, shares exciting details on a human, in vitro model being co-developed by MIT, the NIH National Center for Advancing Translational Sciences, and the National Aeronautics and Space Administration. This model is being developed to study the effects of microgravity and radiation on the International Space Station.

Topics include:

  • Osteoarthritis, post-traumatic osteoarthritis, and how this model resulted from extensive studies on Earth
  • How this Human Cartilage-Osteo-Microphysiological System may hold the keys to the progression of post-traumatic osteoarthritis caused by traumatic joint injuries
  • Uses for this in vitro model in drug discovery and disease modeling