LifeSciences LifeSciences Outer Line LifeSciences Outer Dot
LifeSciences
LifeSciences Outer Line LifeSciences Outer Dot
Truvivo Hepatic system
PIONEERING
ALL-HUMAN
2D+ HEPATIC SYSTEM

TruVivo™ is the first and only 2D+ hepatic system to provide human-relevant, reliable results in an easy-to-use format. TruVivo kits include prequalified primary human cells combined at an optimized ratio to mimic the microarchitecture and functionality of the human liver. TruVivo’s unique combination of relevance, reliability, and simplicity make it ideal for the widest range of potential applications, including metabolism of low-clearance compounds, disease modeling, toxicity testing, and more.

ALL-HUMAN 2D+ HEPATIC SYSTEM
HTS Left Image circle
HTS Right Image

This pioneering 2D+ system combines the best features of 2D and 3D models. With TruVivo, users can expect the simplicity and flexibility of a 2D model, along with the relevance, longevity, architectural integrity, and robustness of a 3D model. 

This combination of attributes makes TruVivo a valuable tool in ADME/DMPK, toxicology, and disease modeling applications for the pharmaceutical and agriscience industries.

TruRELEVANCE Image Outer Line Outer Dot
TruRELEVANCE

TruVivo is the most human-relevant 2D+ hepatic system available because of its 100% human cell composition. Prequalified primary human hepatocytes, stromal, and endothelial cells self-assemble to form in vivo-like hepatocyte colonies with extensive cell-cell connections, including tight and gap junctions and bile canalicular networks. Albumin and urea production are within human physiologically relevant ranges, and Phase I and II metabolic pathways are sustained for at least two weeks.

TruRELIABILITY

TruVivo offers accurate, consistent results — for the greatest level of reliability available today in human hepatic studies. TruVivo’s reliability is proven by consistent urea and albumin production from well to well, experiment to experiment, and user to user. Our process for prequalifying the primary human hepatocytes used in the system is a key factor that powers this unparalleled reliability.

TruREPRODUCIBILITY Image circle Outer Dot Outer Line
TruLONGEVITY Image Outer Dot
TruSIMPLICITY

TruVivo is easy to use and adopt compared to other liver systems. TruVivo uses standard equipment and plate formats, along with cryopreserved cells that accommodate the user's timeline and workflow. Minimal training is required for users with basic cell culture skills.

TruLONGEVITY

TruVivo offers an extended culture period, thanks to prequalified hepatocytes that remain stable for up to six weeks. Morphology, cell polarization, and urea and albumin production are all maintained – making TruVivo an ideal platform for drug discovery and development applications that require prolonged or repeated compound exposures.

TruCUSTOMIZATION Image circle Outer Dot
TruCONVENIENCE Image Outer Line Outer Dot
TruFLEXIBILITY

TruVivo is the most flexible and adaptable hepatic model on the market today. Experiments can begin in as little as five days after culture setup. The system can also be adapted to meet your assay needs, including seeding densities, media changes, and more.

Try Truvivo Overlay Try Truvivo Outer Line Try Truvivo Outer Dot
TRY TRUVIVO
WHAT'S IN THE KIT

The TruVivo kit includes prequalified cryopreserved primary human hepatocytes, primary human feeder cells, and optimized media components to support at least two weeks in culture.

HOW TRUVIVO IS SHIPPED

Same- or next-day shipping is offered to most locations worldwide. Cells are shipped in the vapor phase of liquid nitrogen. Media components are shipped on dry ice or refrigerated cold packs.

WHAT CAN BE ORDERED

TruVivo is available in 24-well and 96-well formats. Complete, ready-to-use kits and negative control kits (containing feeder cells and necessary media) are available.

WHAT TO EXPECT

Users will receive easy-to-follow instructions and personalized support. Our scientific team can help with everything from initial training and lot selection to troubleshooting.

Try Truvivo Left Overlay
CONTACT US

Have a question? Interested in learning more about TruVivo? Our team of experts are ready to help you take the all-human approach to your research. 

Fill out the form below or call 1-888-847-7831, ext. 2000.

circle linecirclecircle
FAQS
Footer portfolio OverlayFooter portfolio Outer LineFooter portfolio Outer DotPortfolio Banner
PORTFOLIO OF ALL-HUMAN    
CELL SOLUTIONS

LifeNet Health’s portfolio of pioneering all-human cell solutions are leading the way in human in vitro biology. Connect with our team of experts to discover how our cutting-edge cell solutions can work for your research applications.